Expanding our Potential via Strategic Collaborations
Collaborations are an important means to executing on our strategy and develop drug candidates that can bring best-in-class therapies to patients.
If you or your company are interested in collaboration and partnering opportunities, contact us.
BeiGene, Ltd. – Zandelisib Clinical Collaboration
In October 2018, we announced a clinical collaboration with BeiGene, Ltd. to evaluate the safety and efficacy of zandelisib (ME-401) in combination with BeiGene’s zanubrutinib, an investigational inhibitor of Bruton’s tyrosine kinase (“BTK”), for the treatment of patients with B-cell malignancies. Study costs will be shared equally by the parties, and we will supply zandelisib and BeiGene will supply zanubrutinib. We retain full commercial rights for zandelisib and BeiGene retains full commercial rights for zanubrutinib.
Helsinn Healthcare SA – Pracinostat Worldwide License
In August 2016, we entered into an exclusive worldwide license, development, manufacturing and commercialization agreement with Helsinn Healthcare SA, for pracinostat in acute myeloid leukemia, myelodysplastic syndrome and other potential indications. Under the agreement, Helsinn holds a worldwide exclusive license to develop, manufacture and commercialize pracinostat, and is primarily responsible for funding its global development and commercialization. Pursuant to the agreement, we received payments of $20.0 million and we are eligible to receive up to $444 million in potential regulatory and sales-based milestones, along with royalty payments on the net sales of pracinostat, which, in the U.S., are tiered and begin in the mid-teens.